Moleküler Biyoloji ve Genetik Seminerleri: Dr. Öğr. Üyesi Ertuğrul Dalgıç
Moleküler Biyoloji ve Genetik Bölümümüzün başlattığı seminer serisinin yeni, Zonguldak Bülent Ecevit Üniversitesi Medikal Biyoloji Bölümü’nden Dr. Öğr. Üyesi Ertuğrul Dalgıç.
Dr. Dalgıç’ın “Molecular Networks of Human Diseases“ başlıklı konuşmasını 28 Şubat Pazartesi saat 13:00’ten itibaren Zoom üzerinden takip edebilirsiniz.
Özet: Molecular and cellular understanding of human diseases is dependent on network analysis since there are intricate relationships at various levels. Analysis of gene expression correlation networks showed that tumor sample based networks are significantly less connected than paired normal networks. No common list of differentially connected genes was found among different tumor networks. Putative antagonist protein pairs with mutual inhibition were also analyzed across several cancer samples or cancer types. Analysis of two different datasets suggested that a few proteins are enriched in most of the antagonistic relationships. Some specific types of cancer are more frequently associated with these proteins. Systems level analysis of network properties makes important contributions to our understanding of human diseases.
Konuşmacı Hakkında: Ertuğrul Dalgıç graduated from Bilkent University Department of Molecular Biology in 2004. He received his Master’s degree from the same department in 2006. He finished his PhD for Cell and Molecular Biology at Michigan State University in 2012. He received Quantitative Biology and Modelling Initiative Fellowship during his PhD studies. He was a teaching assistant for System Biology seminar course and also a mentor for Undergraduate Research Training Program for Biological and Mathematical Sciences at Michigan State University. He was a Postdoctoral Research Fellow at Cold Spring Harbor Laboratory until 2013. He joined the Department of Medical Biology at Zonguldak Bülent Ecevit University School of Medicine as an assistant professor in 2014. He has been teaching Medical Biology, Systems Biology and Bioinformatics courses in the Schools of Medicine, Dentistry, Pharmacy, and the Department of Molecular Biology and Genetics. He had a TUBITAK supported reintegration project entitled “Topological analysis of intracellular cancer networks,” which ended in 2017. He has also been working as a consultant for private research companies for systems biology project. He was a part-time lecturer in Kadir Has University Department of Molecular Biology and Genetics in 2021 Fall Semester.