Molecular Biology and Genetics Seminars: Asst. Prof. Ertuğrul Dalgıç

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Asst. Prof. Ertuğrul Dalgıç from Zonguldak Bülent Ecevit University will be the next guest of the seminar series organized by KHAS Molecular Biology and Genetics Department with his speech Molecular Networks of Human Diseases” on Monday, February 28 at 13.00.

The event will take place on Zoom and is open to anyone interested.

Abstract: Molecular and cellular understanding of human diseases is dependent on network analysis since there are intricate relationships at various levels. Analysis of gene expression correlation networks showed that tumor sample based networks are significantly less connected than paired normal networks. No common list of differentially connected genes was found among different tumor networks. Putative antagonist protein pairs with mutual inhibition were also analyzed across several cancer samples or cancer types. Analysis of two different datasets suggested that a few proteins are enriched in most of the antagonistic relationships. Some specific types of cancer are more frequently associated with these proteins. Systems level analysis of network properties makes important contributions to our understanding of human diseases.

About of Speaker: Ertuğrul Dalgıç graduated from Bilkent University Department of Molecular Biology in 2004. He received his Master’s degree from the same department in 2006. He finished his PhD for Cell and Molecular Biology at Michigan State University in 2012. He received Quantitative Biology and Modelling Initiative Fellowship during his PhD studies. He was a teaching assistant for System Biology seminar course and also a mentor for Undergraduate Research Training Program for Biological and Mathematical Sciences at Michigan State University. He was a Postdoctoral Research Fellow at Cold Spring Harbor Laboratory until 2013. He joined the Department of Medical Biology at Zonguldak Bülent Ecevit University School of Medicine as an assistant professor in 2014. He has been teaching Medical Biology, Systems Biology and Bioinformatics courses in the Schools of Medicine, Dentistry, Pharmacy, and the Department of Molecular Biology and Genetics. He had a TUBITAK supported reintegration project entitled “Topological analysis of intracellular cancer networks,” which ended in 2017. He has also been working as a consultant for private research companies for systems biology project. He was a part-time lecturer in Kadir Has University Department of Molecular Biology and Genetics in 2021 Fall Semester.

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